Search
Invitrogen
HIST1H2BJ Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
FIGURE: 1 / 6
HIST1H2BJ Antibody (PA5-24220) in IHC (P)
Immunohistochemistry analysis of HIST1H2BJ in formalin fixed and paraffin embedded human hepatocarcinoma. Samples were incubated with HIST1H2BJ polyclonal antibody (Product # PA5-24220) followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of this antibody for immunohistochemistry. Clinical relevance has not been evaluated.
Product Details
PA5-24220
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide between 57-86 amino acids from the central region of human HIST1H2BJ
Conjugate
Form
Liquid
Concentration
0.4 mg/mL
Amount
160 µg
Purification
Protein A, Antigen affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This antibody is predicted to react with bovine, chicken, mouse, non-human primate, rat and Xenopus and zebrafish based on sequence homology.
Target Information
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bpof DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2B family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the histone microcluster on chromosome 6p21.33.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: H2B histone family, member R; H2B/r; histone 1, H2bj; histone cluster 1 H2B family member j; histone cluster 1, H2bj; Histone H2B type 1-J; Histone H2B.1; Histone H2B.r; unnamed protein product
Gene Aliases: H2B/r; H2BC11; H2BFR; H2BJ; HIST1H2BJ
UniProt ID: (Human) P06899
Entrez Gene ID: (Human) 8970
innate immune response in mucosa
chromatin organization
nucleosome assembly
negative regulation of tumor necrosis factor-mediated signaling pathway
antibacterial humoral response
killing of cells of other organism
defense response to bacterium
defense response to Gram-negative bacterium
defense response to Gram-positive bacterium
protein localization to CENP-A containing chromatin
antimicrobial humoral immune response mediated by antimicrobial peptide
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support