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Invitrogen
TC10 Polyclonal Antibody
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FIGURE: 1 / 2
TC10 Antibody (PA5-25749) in IHC (P)
Immunohistochemistry analysis of TC10 in formalin fixed and paraffin embedded human brain tissue. Samples were incubated with TC10 polyclonal antibody (Product # PA5-25749) followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of this antibody for immunohistochemistry. Clinical relevance has not been evaluated.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-25749
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide between 48-76 amino acids from the central region of human TC10
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.5 mg/mL
Amount
200 µg
Purification
Protein A, Antigen affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This antibody is predicted to react with bovine, chicken, canine, equine, mouse, porcine, non-human primate, rat and yeast based on sequence homology.
Target Information
TC10 is a member of the RAS superfamily of small GTP-binding proteins (see HRAS, MIM 190020) involved in insulin-stimulated glucose uptake.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: epididymis secretory protein Li 42; ras homolog gene family, member Q; ras-like protein; ras-like protein family member 7A; ras-like protein TC10; RAS-like, family 7, member A
Gene Aliases: ARHQ; HEL-S-42; RASL7A; TC10; TC10A
UniProt ID: (Human) P17081
Entrez Gene ID: (Human) 23433
endocytosis
actin filament organization
signal transduction
small GTPase mediated signal transduction
insulin receptor signaling pathway
establishment of cell polarity
actin cytoskeleton organization
cortical actin cytoskeleton organization
cellular response to insulin stimulus
regulation of actin cytoskeleton organization
positive regulation of transcription from RNA polymerase II promoter
GTP metabolic process
positive regulation of glucose import
positive regulation of filopodium assembly
negative regulation of protein localization to plasma membrane
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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