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Invitrogen
Phospho-DGCR8 (Ser377) Polyclonal Antibody
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FIGURE: 1 / 1
Phospho-DGCR8 (Ser377) Antibody (PA5-35385) in WB
Western blot of DGCR8 in mouse nuclei lysate showing specific immunolabeling of a band at ~120 kDa corresponding to Phospho-DGCR8 (Ser377) polyclonal antibody (Product # PA5-35385) at in the first lane (-). Phosphospecificity is shown in the second lane (+) where immunolabeling is blocked by pre-adsorption of the phosphopeptide used as the antigen, but not by the corresponding non-phosphopeptide (not shown)... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-35385
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser377 of human DGCR8 conjugated to KLH
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
~0.25 mg/mL
Purification
Affinity chromatography
Storage buffer
0.01M HEPES, pH 7.5, with 0.15M NaCl, 0.1mg/mL BSA, 50% glycerol
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This antibody contains enough material to conduct 10 mini-Western blots.
Target Information
This gene encodes a subunit of the microprocessor complex which mediates the biogenesis of microRNAs from the primary microRNA transcript. The encoded protein is a double-stranded RNA binding protein that functions as the non-catalytic subunit of the microprocessor complex. This protein is required for binding the double-stranded RNA substrate and facilitates cleavage of the RNA by the ribonuclease III protein, Drosha. Alternate splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: DiGeorge syndrome critical region 8; diGeorge syndrome critical region 8 homolog; DiGeorge syndrome critical region gene 8; Em:AC006547.4; unnamed protein product
Gene Aliases: C22orf12; D16H22S1742E; D16H22S788E; D16Wis2; DGCRK6; Gy1; mir-1306; N41; pasha; Vo59c07
UniProt ID: (Human) Q8WYQ5, (Mouse) Q9EQM6
Entrez Gene ID: (Human) 54487, (Mouse) 94223
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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