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          • Primary Antibodies ›
          • EphA2/EphA3/EphA4 Antibodies

          Invitrogen

          EphA2/EphA3/EphA4 Polyclonal Antibody

          1 Published Figure
          1 Reference
          View all (2) EphA2/EphA3/EphA4 antibodies

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          Cite EphA2/EphA3/EphA4 Polyclonal Antibody

          Additional Information:

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          • Antibody Testing Data (1)
          • Published Figures (1)
          EphA2/EphA3/EphA4 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.
          EphA2/EphA3/EphA4 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.

          FIGURE: 1 / 2

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          EphA2/EphA3/EphA4 Antibody (PA5-36108) in WB

          Western blot analysis of EphA2/EphA3/EphA4 in Lane 1: HeLa whole cell lysate (40 µg), Lane 2: HEK293T whole cell lysate (40 µg), Lane 3: MEF whole cell lysate (40 µg), Lane 4: C6 whole cell lysate (40 µg), Lane 5: PC12 whole cell lysate (40 µg). Samples were incubated with EphA2/EphA3/EphA4 polyclonal antibody (Product # PA5-36108) at a dilution of 1:500. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
          Published figure supplied by benchsci-logo
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          View Product

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          EphA2/EphA3/EphA4 Antibody in Western Blot (WB)
          EphA2/EphA3/EphA4 Antibody in Immunohistochemistry (IHC)

          Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.

          EphA2/EphA3/EphA4 Polyclonal Antibody

          Product Details

          PA5-36108

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:1,000
          -

          Immunohistochemistry (IHC)

          -
          View 1 publication 1 publication

          Immunocytochemistry (ICC/IF)

          1:50-1:200
          -
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Synthetic peptide corresponding to amino acids 550-600 of human EphA2
          3D Epitope / Immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Amount

          100 µg

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.2, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2553372

          Product Specific Information

          This antibody detects endogenous protein at a molecular weight of 112 kDa.

          Purity is >95% by SDS-PAGE.

          Target Information

          The Eph subfamily represents the largest group of receptor protein tyrosine kinases identified to date. While the biological activities of these receptors have yet to be determined, there is increasing evidence that they are involved in central nervous system function and in development. The Eph subfamily receptors of human origin (and their murine/avian homologs) include EphA1(Eph), EphA2 (Eck), EphA3 (Hek4), EphA4 (Hek8), EphA5 (Hek7), EphA6 (Hek12),EphA7 (Hek11/MDK1), EphA8 (Hek3), EphB1 (Hek6), EphB2 (Hek5), EphB3(Cek10, Hek2), EphB4 (Htk), EphB5 (Hek9) and EphB6 (Mep). Ligands for Eph receptors include ephrin-A4 (LERK-4) which binds EphA3 and EphB1. In addition, Ephrin-A2 (Elf-1) has been described as the ligand for EphA4, ephrin-A3 (Ehk1-L) as the ligand for EphA5 and ephrin-B2 (Htk-L) as the ligand for EphB4 (Htk).

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: ECK; EK4; EPH-like kinase 4; EPH-like kinase 8; eph-like tyrosine kinase 1; Eph-related receptor protein tyrosine kinase; Ephrin A2; Ephrin A3; Ephrin A4; ephrin receptor EphA2; EphrinA2; EphrinA3; EphrinA4; epithelial cell kinase; epithelial cell receptor protein tyrosine kinase; human embryo kinase 1; receptor protein-tyrosine kinase HEK8; rEK4; Sek-2; soluble receptor; testicular tissue protein Li 64; TYRO1 protein tyrosine kinase; TYRO4 protein tyrosine kinase; tyrosine-protein kinase receptor ECK; tyrosine-protein kinase receptor ETK1; tyrosine-protein kinase receptor MPK-3; tyrosine-protein kinase receptor MPK-5; tyrosine-protein kinase receptor REK4; tyrosine-protein kinase receptor SEK; tyrosine-protein kinase receptor SEK-1; tyrosine-protein kinase receptor SEK-2; tyrosine-protein kinase TYRO1; tyrosine-protein kinase TYRO4; unnamed protein product

          View more View less

          Gene Aliases: 2900005C20Rik; ARCC2; Cek4; Cek8; CTPA; CTPP1; CTRCT6; ECK; EK4; EK8; End3; ETK; ETK1; HEK; HEK4; HEK8; Mek4; Myk2; rb; RGD1560587; SEK; Sek-2; Sek1; Sek2; TYRO1; TYRO4

          View more View less

          UniProt ID: (Human) P29317, (Human) P29320, (Human) P54764, (Mouse) Q03145, (Rat) O08680, (Mouse) Q03137

          View more View less

          Entrez Gene ID: (Human) 1969, (Human) 2042, (Human) 2043, (Mouse) 13836, (Rat) 366492, (Rat) 29210, (Mouse) 13837, (Mouse) 13838, (Rat) 316539

          View more View less

          Function(s)
          protein kinase activity protein tyrosine kinase activity transmembrane receptor protein tyrosine kinase activity ephrin receptor activity protein binding ATP binding growth factor binding cadherin binding molecular function activator activity GPI-linked ephrin receptor activity transmembrane-ephrin receptor activity beta-amyloid binding kinase activity PH domain binding identical protein binding ephrin receptor binding DH domain binding protein tyrosine kinase binding nucleotide binding
          Process(es)
          fever generation transmembrane receptor protein tyrosine kinase signaling pathway axon guidance motor neuron axon guidance regulation of epithelial to mesenchymal transition negative regulation of epithelial to mesenchymal transition positive regulation of neuron projection development negative regulation of neuron projection development cell migration peptidyl-tyrosine phosphorylation regulation of cell-cell adhesion regulation of cell migration response to lipopolysaccharide regulation of actin cytoskeleton organization negative regulation of endocytosis ephrin receptor signaling pathway regulation of focal adhesion assembly regulation of microtubule cytoskeleton organization cellular response to retinoic acid cellular response to interleukin-1 cellular response to follicle-stimulating hormone stimulus fasciculation of sensory neuron axon fasciculation of motor neuron axon synaptic membrane adhesion positive regulation of protein localization to plasma membrane regulation of developmental process synapse organization deadenylation-dependent decapping of nuclear-transcribed mRNA negative regulation of cell adhesion adult walking behavior positive regulation of cell proliferation glial cell migration negative regulation of translation central nervous system projection neuron axonogenesis corticospinal tract morphogenesis positive regulation of cell migration negative regulation of cell migration adherens junction organization regulation of GTPase activity negative regulation of neuron apoptotic process positive regulation of cell adhesion negative regulation of translational initiation positive regulation of JNK cascade animal organ development negative regulation of axon regeneration regulation of astrocyte differentiation regulation of axonogenesis positive regulation of dendrite morphogenesis protein stabilization innervation regulation of dendritic spine morphogenesis negative regulation of ERK1 and ERK2 cascade nephric duct morphogenesis cochlea development neuron projection guidance synapse pruning neuron projection fasciculation membraneless organelle assembly negative regulation of cellular response to hypoxia negative regulation of long-term synaptic potentiation cellular response to oxygen-containing compound positive regulation of beta-amyloid formation positive regulation of intracellular signal transduction positive regulation of amyloid precursor protein catabolic process cellular response to beta-amyloid positive regulation of leukocyte adhesion to arterial endothelial cell regulation of modification of synaptic structure regulation of synapse pruning central nervous system development neuron projection development skeletal system development angiogenesis blood vessel development vasculogenesis osteoblast differentiation negative regulation of cytokine production blood vessel endothelial cell proliferation involved in sprouting angiogenesis response to stress inflammatory response intrinsic apoptotic signaling pathway in response to DNA damage regulation of lamellipodium assembly notochord formation negative regulation of angiogenesis neural tube development neuron differentiation keratinocyte differentiation osteoclast differentiation epithelial cell differentiation negative regulation of chemokine production mammary gland epithelial cell proliferation regulation of cell adhesion mediated by integrin negative regulation of cell adhesion mediated by integrin post-anal tail morphogenesis regulation of blood vessel endothelial cell migration regulation of angiogenesis cAMP metabolic process bone remodeling axial mesoderm formation blood vessel morphogenesis notochord morphogenesis cell motility defense response to Gram-positive bacterium notochord cell development cell chemotaxis branching involved in mammary gland duct morphogenesis lens fiber cell morphogenesis regulation of ERK1 and ERK2 cascade response to growth factor protein localization to plasma membrane activation of GTPase activity negative regulation of lymphangiogenesis positive regulation of bicellular tight junction assembly pericyte cell differentiation regulation of cell adhesion
          It has to be done as per old AB suggested Products section.

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