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FIGURE: 1 / 2
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
This antibody detects endogenous protein at a molecular weight of 50 kDa.
Purity is >95% by SDS-PAGE.
Collapsin response mediator proteins (CRMPs), including CRMP-1 (DRP-1), CRMP-2 (DRP-2 or TOAD64), CRMP-3 (DRP-4), CRMP-4 (DRP-3) and CRMP-5 (DRP-5), mediate signal transduction after exposure of neural cells to the axon guidance molecule Semaphorin 3A (SEMA3A)/collapsin. CRMPs are present in the developing cerebral cortex and neocortical neurons and are responsive to SEMA3A. In the adult brain, the expression of CRMPs is dramatically downregulated. However, they remain expressed in structures that retain their capacity for differentiation and plasticity. CRMP-3 is expressed transiently in developing spinal cord and selectively in the postnatal cerebellum.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Collapsin response mediator protein 3; CRMP-3; DRP-4; ULIP-4; ULIP4 protein; unc-33-like phosphoprotein 4; UNC33-like phosphoprotein 4; unnamed protein product
Gene Aliases: CRMP-3; CRMP3; DPY4; Dpys4; DRP-4; ULIP4
UniProt ID: (Human) O14531, (Rat) Q62951
Entrez Gene ID: (Human) 10570, (Rat) 25417, (Mouse) 26757
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