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Invitrogen
Plexin A2 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-37199
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to residues in human PLXNA2
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This antibody detects endogenous protein at a molecular weight of 237 kDa.
Purity is >95% by SDS-PAGE.
Target Information
Plexins are a family of large, transmembrane receptors for multiple classes of semaphorins in vertebrates. Plexins are widely expressed, and regions of their extracellular domain are homologus to both scatter factor receptors and semaphorin domains. Plexins may act as semaphorin receptors alone or in combination with neuropilins. Plexins are divided into four subfamilies designated plexin-A, -B, -C, and -D. Drosophila plexin-A is a receptor for class I semaphorins and controls motor and axon guidance. Plexin-A3 mediates cell-repelling cues. Plexins B and C are receptors for Sema 4 and Sema 7, respectively.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FLJ11751; FLJ30634; plex 2; plexin 2; plexin-2; semaphorin receptor OCT; transmembrane protein OCT; unnamed protein product
Gene Aliases: 2810428A13Rik; mKIAA0463; OCT; PlexA2; PLXN2
UniProt ID: (Human) O75051, (Mouse) P70207
Entrez Gene ID: (Human) 5362, (Rat) 289392, (Mouse) 18845
somitogenesis
cell surface receptor signaling pathway
nervous system development
synapse assembly
anatomical structure morphogenesis
neural tube development
regulation of cell migration
tube development
animal organ development
pharyngeal system development
limb bud formation
semaphorin-plexin signaling pathway
brain development
cerebellar granule cell precursor tangential migration
regulation of locomotion
centrosome localization
epithelium development
regulation of plasma membrane bounded cell projection organization
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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