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Invitrogen
DBC1 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-37959
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Peptide with sequence C-ESHNRFSATEVTNK, from the internal region of CCAR2 (aa842-855)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Ammonium sulfate precipitation
Storage buffer
TBS, pH 7.3, with 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This antibody is predicted to react with mouse, rat, dog, pig and cow based on sequence homology.
This antibody is tested in Peptide ELISA: antibody detection limit dilution 64,000.
Target Information
DBC1 is located within a chromosomal region that shows loss of heterozygosity in some bladder cancers. It contains a 5' CpG island that may be a frequent target of hypermethylation, and it may undergo hypermethylation-based silencing in some bladder cancers.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: cell division cycle and apoptosis regulator protein 2; DBC.1; DBCCR1; deleted in breast cancer 1; FAM5A; putative protein from MH0802201; unnamed protein product
Gene Aliases: 2610301G19Rik; DBC-1; DBC1; KIAA1967; mKIAA1967; NET35; p30 DBC; p30DBC
UniProt ID: (Human) Q8N163, (Mouse) Q8VDP4
Entrez Gene ID: (Human) 57805, (Mouse) 219158
regulation of transcription, DNA-templated
RNA splicing
response to UV
negative regulation of cell growth
regulation of protein stability
negative regulation of proteasomal ubiquitin-dependent protein catabolic process
regulation of DNA-templated transcription, elongation
regulation of circadian rhythm
positive regulation of apoptotic process
negative regulation of catalytic activity
regulation of RNA splicing
mitochondrial fragmentation involved in apoptotic process
negative regulation of transcription, DNA-templated
positive regulation of canonical Wnt signaling pathway
regulation of protein deacetylation
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
positive regulation of DNA damage checkpoint
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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