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Invitrogen
HTR3B Polyclonal Antibody
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Product Details
PA5-41033
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide directed towards the N-terminal of human HTR3B (aa 8-57).
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Amount
50 µg
Purification
Affinity Chromatography
Storage buffer
PBS with 2% sucrose
Contains
0.09% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Peptide sequence: PLWACILVAA GILATDTHHP QDSALYHLSK QLLQKYHKEV RPVYNWTKAT
Sequence homology: Cow: 79%; Dog: 77%; Guinea Pig: 79%; Human: 100%; Mouse: 77%; Pig: 86%; Rabbit: 86%; Rat: 79%
Target Information
The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit B of the type 3 receptor for 5-hydroxytryptamine, a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 5-HT3 receptor subunit B; 5-HT3-B; 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic; 5-hydroxytryptamine 3 receptor B subunit; 5-hydroxytryptamine receptor 3B; ligand gated receptor subunit; Serotonin receptor 3B; serotonin-gated ion channel subunit; unnamed protein product
Gene Aliases: 5-HT3B; HTR3B
UniProt ID: (Human) O95264, (Mouse) Q9JHJ5
Entrez Gene ID: (Human) 9177, (Mouse) 57014
transmembrane signaling receptor activity
ion channel activity
extracellular ligand-gated ion channel activity
excitatory extracellular ligand-gated ion channel activity
ligand-gated ion channel activity
serotonin-gated cation channel activity
transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential
G-protein coupled serotonin receptor activity
serotonin-activated cation-selective channel activity
ligand-gated ion channel
ion transport
serotonin receptor signaling pathway
chemical synaptic transmission
ion transmembrane transport
regulation of membrane potential
regulation of postsynaptic membrane potential
excitatory postsynaptic potential
inorganic cation transmembrane transport
serotonin-gated cation-selective signaling pathway
transport
cation transmembrane transport
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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