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Invitrogen
DPYSL3 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-43752
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide directed towards the middle region of human DPYSL3
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.5 mg/mL
Amount
50 µg
Purification
Affinity Chromatography
Storage buffer
PBS with 2% sucrose
Contains
0.09% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Peptide sequence: VFDLTTTPKG GTPAGSARGS PTRPNPPVRN LHQSGFSLSG TQVDEGVRSA
Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%
Target Information
DPYSL3 is necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. DPYSL3 plays a role in axon guidance, neuronal growth cone collapse and cell migration.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: collapsin response mediator protein 4 long; LCRMP-4; testicular secretory protein Li 7; tuc-4; unc-33-like phosphoprotein 1; unnamed protein product
Gene Aliases: CRMP-4; CRMP4; DRP-3; DRP3; LCRMP; ULIP; ULIP-1
UniProt ID: (Human) Q14195
Entrez Gene ID: (Human) 1809
dihydropyrimidinase activity
protein binding
hydrolase activity
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SH3 domain binding
filamin binding
chondroitin sulfate binding
identical protein binding
phosphoprotein binding
pyrimidine nucleobase catabolic process
positive regulation of neuron projection development
negative regulation of neuron projection development
negative regulation of cell migration
neuron development
response to axon injury
actin filament bundle assembly
positive regulation of filopodium assembly
actin crosslink formation
cellular response to cytokine stimulus
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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