Search
Invitrogen
IL1R1 Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-46930
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Sf 21-derived recombinant human IL-1 RI
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Lyophilized
Concentration
0.2 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5% trehalose
Contains
No Preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Reconstitute at 0.2 mg/mL in sterile PBS.
Endoxin level is <0.10 EU per 1 µg of the antibody by the LAL method.
Target Information
The IL-1 system includes two agonists (IL-1 and IL-1), converting enzymes, antagonists, two receptors (IL-1 RI and IL-1 RII) and the IL-1 receptor accessory protein. Interleukin-1 signal is transduced through the type I receptor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: antigen CD121a; CD121 alpha; CD121 antigen-like family member A; il-1 receptor; il-1r; il1 receptor; interleukin 1 receptor alpha, type I; interleukin 1 receptor precursor; interleukin-1 receptor; interleukin-1 receptor alpha; interleukin-1 receptor type I; unnamed protein product
Gene Aliases: CD121A; CRMO3; D2S1473; IL-1R-alpha; IL-1RT1; IL1R; IL1RA; P80
UniProt ID: (Human) P14778
Entrez Gene ID: (Human) 3554
microglial cell activation involved in immune response
immune response
signal transduction
cell surface receptor signaling pathway
positive regulation of platelet-derived growth factor receptor signaling pathway
smooth muscle adaptation
positive regulation of interferon-gamma production
positive regulation of I-kappaB kinase/NF-kappaB signaling
positive regulation of MAPK cascade
regulation of inflammatory response
negative regulation of inflammatory response
positive regulation of inflammatory response
positive regulation of protein kinase B signaling
interleukin-1-mediated signaling pathway
response to interleukin-1
positive regulation of T-helper 1 cell cytokine production
negative regulation of interleukin-1-mediated signaling pathway
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support