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Invitrogen
CXCL2 Polyclonal Antibody
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FIGURE: 1 / 8
CXCL2 Antibody (PA5-47015) in ICC/IF
Immunocytochemistry analysis of CXCL2 in immersion fixed mouse splenocytes stimulated with LPS and monensin. Samples were incubated in CXCL2 polyclonal antibody (Product # PA5-47015) using a dilution of 10 µg/mL for 3 hours at room temperature followed by NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody (red) and counterstained with DAPI (blue). Specific staining was localized to cytoplasm.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-47015
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse
Published species
Human,
Mouse
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
E. coli-derived recombinant mouse CXCL2/MIP-2 Ala28-Asn100
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Lyophilized
Concentration
0.2 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5% trehalose
Contains
No Preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
In direct ELISAs, approximately 5% cross-reactivity with recombinant human (rh) GRO alpha, rhGRO beta, rhGRO gamma, recombinant rat (rr) CINC-1, rrCINC-2 alpha, rrCINC-2 beta, and rrCINC-3 is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
Endoxin level is <0.10 EU per 1 µg of the antibody by the LAL method.
Target Information
Produced by activated monocytes and neutrophils and expressed at sites of inflammation. Hematoregulatory chemokine, which, in vitro, suppresses hematopoietic progenitor cell proliferation. GRO-beta(5-73) shows a highly enhanced hematopoietic activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: C Cmotif chemokine; C X C motif chemokine; CC motif chemokine; CCmotif chemokine; chemokine (C-X-C motif) ligand 2; CXC; CXC motif chemokine; CXCL; GRO b; gro beta; GRO β; GRObeta; GROβ; macrophage inflammatory protein 2; MIP 2 a; MIP 2 alpha; MIP 2 α; MIP2 a; MIP2 α; small inducible cytokine subfamily, member 2; unnamed protein product
Gene Aliases: CINC-2a; Gro2; GROb; Mgsa-b; MIP-2; MIP-2a; Mip2; Scyb; Scyb2
UniProt ID: (Mouse) P10889
Entrez Gene ID: (Mouse) 20310
response to amphetamine
response to molecule of bacterial origin
chemotaxis
defense response
immune response
positive regulation of cytosolic calcium ion concentration
response to gamma radiation
neutrophil chemotaxis
leukocyte chemotaxis
response to estradiol
response to glucocorticoid
cellular response to lipopolysaccharide
cellular response to interleukin-1
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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