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Invitrogen
RECK Polyclonal Antibody
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FIGURE: 1 / 1
RECK Antibody (PA5-47190) in WB
Western blot analysis of RECK in human liver tissue. Samples were incubated in RECK polyclonal antibody (Product # PA5-47190) using a dilution of 1 µg/mL followed by a HRP-conjugated Anti-Goat IgG secondary antibody. A specific band was detected for RECK at approximately 130 kDa (as indicated). This experiment was conducted under reducing conditions.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-47190
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Mouse myeloma cell line NS0-derived recombinant human RECK Gly27-Val934
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Lyophilized
Concentration
0.2 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5% trehalose
Contains
No Preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
RECK is a cysteine-rich, extracellular protein with protease inhibitor-like domains whose expression is suppressed strongly in many tumors and cells transformed by various kinds of oncogenes. In normal cells, this membrane-anchored glycoprotein may serve as a negative regulator for matrix metalloproteinase-9, a key enzyme involved in tumor invasion and metastasis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: membrane-anchored glycoprotein (metastasis and invasion); ST15; suppression of tumorigenicity 15 (reversion-inducing-cysteine-rich protein with kazal motifs); suppression of tumorigenicity 5 (reversion-inducing-cysteine-rich protein with kazal motifs); suppressor of tumorigenicity 15 protein; unnamed protein product
Gene Aliases: ST15
UniProt ID: (Human) O95980
Entrez Gene ID: (Human) 8434
blood vessel maturation
sprouting angiogenesis
negative regulation of extracellular matrix disassembly
extracellular matrix organization
negative regulation of cell migration
positive regulation of amyloid precursor protein biosynthetic process
regulation of angiogenesis
canonical Wnt signaling pathway
regulation of canonical Wnt signaling pathway
regulation of establishment of blood-brain barrier
positive regulation of canonical Wnt signaling pathway
positive regulation of beta-amyloid formation
regulation of extracellular matrix organization
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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