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Invitrogen
ITGB8 Polyclonal Antibody
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FIGURE: 1 / 2
ITGB8 Antibody (PA5-49404) in IHC (P)
Immunohistochemistry analysis of ITGB8 in paraffin-embedded human heart section. Samples were incubated with ITGB8 polyclonal antibody (Product # PA5-49404) using a dilution of 1:25 followed by an undiluted biotinylated goat polyvalent antibody was used as the secondary, followed by DAB staining.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-49404
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide between 197-231 amino acids from the Central region of human ITGB8.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
2 mg/mL
Amount
800 µg
Purification
Antigen affinity chromatography, Protein A
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Predicted to react with rabbit based on sequence homology.
Target Information
ITGB8 (Integrin beta 8) is a member of the integrin beta chain family and is a single-pass type I membrane protein with a VWFA domain and four cysteine-rich repeats. This protein noncovalently binds to an alpha subunit to form a heterodimeric integrin complex. In general, integrin complexes mediate cell-cell and cell-extracellular matrix interactions and this complex plays a role in human airway epithelial proliferation. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Integrin beta8; unnamed protein product
UniProt ID: (Human) P26012
Entrez Gene ID: (Human) 3696
vasculogenesis
cell adhesion
cell-matrix adhesion
cell surface receptor signaling pathway
integrin-mediated signaling pathway
anatomical structure morphogenesis
positive regulation of gene expression
negative regulation of gene expression
cell migration
cell differentiation
cell adhesion mediated by integrin
positive regulation of angiogenesis
cartilage development
placenta blood vessel development
cell-cell adhesion
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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