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Invitrogen
Noto Polyclonal Antibody
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FIGURE: 1 / 2
Noto Antibody (PA5-49419) in WB
Western blot analysis of Noto in mouse liver, mouse pancreas tissue lysate (from left to right). Samples were incubated with Noto polyclonal antibody (Product # PA5-49419) using a dilution of 1:4,000 followed by goat anti-rabbit IgG H&L (HRP) at a dilution of 1:10,000. Lysates at 20 µg per lane.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-49419
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide between 200-234 amino acids from the C-terminal region of Mouse Noto.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Purification
Protein A, Antigen affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
Transcription regulator acting downstream of both FOXA2 and T during notochord development. Required for node morphogenesis. Is essential for cilia formation in the posterior notochord (PNC) and for left-right patterning; acts upstream of FOXJ1 and RFX3 in this process and is required for the expression of various components important for axonemal assembly and function. Plays a role in regulating axial versus paraxial cell fate.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: floating head homolog; Not homeodomain protein; notochord homolog; truncate; unnamed protein product
Gene Aliases: Flh; MmNot; Not; tc
UniProt ID: (Mouse) Q5TIS6
Entrez Gene ID: (Mouse) 384452
heart looping
regulation of transcription from RNA polymerase II promoter
determination of left/right symmetry
central nervous system development
brain development
embryonic pattern specification
dorsal/ventral pattern formation
neuron differentiation
notochord development
motile cilium assembly
regulation of cilium assembly
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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