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Invitrogen
BAG5 Polyclonal Antibody
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FIGURE: 1 / 1
BAG5 Antibody (PA5-49696) in WB
Western Blot analysis of BAG5 was performed using Lane 1: A549 cells lysate. Lane 2: HeLa cells lysate. Lane 3: 293T cells lysate. Lysates: per lane. The membrane was probed with BAG5 Polyclonal Antibody (Product # PA5-49696) using 1:500 dilution. Secondary antibody: Donkey anti Rabbit IgG - H&L (HRP) at 1:3,000 dilution. Exposure time: 1 minute.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-49696
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Fusion protein corresponding to C terminal 350 amino acids of Human Bcl-2-associated athanogene 5
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.3 mg/mL
Amount
30 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 40% glycerol
Contains
0.05% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
The antibody detects endogenous level of total BAG5 protein.
Target Information
It has been hypothesizes that the BAG-5 protein will induce the death of nigral neurons through its predicted interaction with hsp70, which will cause increased protein aggregation and cell death by disinhibition of hsp70's anti-apoptotic function. It is believed that BAG-5 will play an important role in the mechanisms of neuronal death. BAG-5 may also be of interest due to its possible role as a modulator of the hsp70/hsp40 chaperone axis or its possible interaction and coordination of localization/ modulation of other BAG containing proteins via BAG-BAG heterodimerization.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: bcl-2-associated athanogene 5; BCL2 associated athanogene 5; unnamed protein product
Gene Aliases: BAG-5; CMD2F
UniProt ID: (Human) Q9UL15
Entrez Gene ID: (Human) 9529
protein folding
Golgi organization
negative regulation of neuron projection development
negative regulation of protein ubiquitination
negative regulation of proteasomal ubiquitin-dependent protein catabolic process
protein stabilization
negative regulation of protein refolding
regulation of inclusion body assembly
negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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