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Invitrogen
PLXNB1 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-50732
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to a region derived from internal residues of human plexin B1
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
2.7 mg/mL
Amount
270 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 40% glycerol
Contains
0.05% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
The antibody detects endogenous levels of total Plexin B1 / PLXNB1 protein.
Target Information
Plexin B1 is a protein of the plexin family that in humans is encoded by the PLXNB1gene. Receptor for SEMA4D. Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: KIAA0407; plexin 1; plexin 5; plexin-A1; semaphorin receptor SEP; unnamed protein product
Gene Aliases: PLEXIN-B1; PLXN5; SEP
UniProt ID: (Human) O43157
Entrez Gene ID: (Human) 5364
negative regulation of cell adhesion
synapse assembly
regulation of cell shape
cell migration
regulation of cell migration
negative regulation of osteoblast proliferation
positive regulation of Rho protein signal transduction
intracellular signal transduction
positive regulation of GTPase activity
ossification involved in bone maturation
neuron projection morphogenesis
positive regulation of axonogenesis
regulation of cytoskeleton organization
positive regulation of protein kinase B signaling
semaphorin-plexin signaling pathway
inhibitory synapse assembly
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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