Search
Invitrogen
BOK Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
{{$ctrl.translations['antibody.pdp.skuNotes.additionalInformation']}}:
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-50820
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide of human BCL2-related ovarian killer
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1.4 mg/mL
Amount
140 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 40% glycerol
Contains
0.05% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
The antibody detects endogenous levels of total BOK protein.
Target Information
The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein contains all four BCL-2 like domains and is a pro-apoptotic BCL-2 protein identified in the ovary.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: bcl-2-like protein 9; BCL2 family apoptosis regulator; BCL2 related ovarian killer; bcl2-L-9; BOK, BCL2 family apoptosis regulator; hBOK
Gene Aliases: BCL2L9; BOKL
UniProt ID: (Human) Q9UMX3
Entrez Gene ID: (Human) 666
release of cytochrome c from mitochondria
apoptotic process
cellular component disassembly involved in execution phase of apoptosis
male gonad development
intrinsic apoptotic signaling pathway in response to DNA damage
regulation of autophagy
regulation of apoptotic process
positive regulation of apoptotic process
negative regulation of apoptotic process
negative regulation of neuron apoptotic process
oligodendrocyte differentiation
protein oligomerization
regulation of cytosolic calcium ion concentration
negative regulation of mitochondrial depolarization
transmembrane transport
negative regulation of necroptotic process
intrinsic apoptotic signaling pathway by p53 class mediator
response to cisplatin
extrinsic apoptotic signaling pathway in absence of ligand
positive regulation of execution phase of apoptosis
negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
regulation of chorionic trophoblast cell proliferation
positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
positive regulation of PERK-mediated unfolded protein response
regulation of granulosa cell apoptotic process
positive regulation of intrinsic apoptotic signaling pathway
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support