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Invitrogen
C1QBP Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-50922
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthesized peptide derived from the Internal region of human C1QBP.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 0.5% BSA, 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
C1QBP Polyclonal Antibody detects endogenous levels of C1QBP protein.
Target Information
Replication Protein A (RPA) (also known as human single-stranded DNA binding protein, or HSSB) is involved in DNA replication, repair, and recombination. RPA from human cells is a stable heterotrimer of 70kDa, 32-34kDa, and 11-14kDa subunits (RPA70, RPA32, and RPA14 respectively). RPA is required for the SV40 large tumor antigen-catalyzed unwinding of SV40 DNA and stimulates DNA polymerase alpha and delta. RPA34 is phosphorylated at the G1/S boundary of the cell cycle or upon exposure of cells to DNA damage-inducing agents including ionizing and UV radiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ASF/SF2-associated protein p32; C1q globular domain-binding protein; complement component 1, q subcomponent binding protein; GC1q-R protein; glycoprotein gC1qBP; hyaluronan-binding protein 1; mitochondrial matrix protein p32; p33; RPA; splicing factor SF2-associated protein; unnamed protein product
Gene Aliases: COXPD33; D11Wsu182e; gC1Q-R; GC1QBP; gC1qR; HABP1; P32; SF2AP32; SF2p32
UniProt ID: (Human) Q07021, (Rat) O35796
Entrez Gene ID: (Human) 708, (Rat) 29681, (Mouse) 12261
complement component C1q binding
transcription corepressor activity
mRNA binding
enzyme inhibitor activity
protein kinase C binding
protein binding
hyaluronic acid binding
transcription factor binding
kininogen binding
adrenergic receptor binding
C5-methylcytidine-containing RNA reader activity
mitochondrial ribosome binding
deoxyribonuclease inhibitor activity
negative regulation of transcription from RNA polymerase II promoter
mitochondrial RNA catabolic process
immune response
regulation of complement activation
negative regulation of interferon-gamma production
negative regulation of interleukin-12 production
negative regulation of MDA-5 signaling pathway
negative regulation of RIG-I signaling pathway
mature ribosome assembly
positive regulation of apoptotic process
protein kinase B signaling
positive regulation of cell adhesion
negative regulation of mRNA splicing, via spliceosome
negative regulation of defense response to virus
positive regulation of protein kinase B signaling
positive regulation of mitochondrial translation
positive regulation of neutrophil chemotaxis
positive regulation of substrate adhesion-dependent cell spreading
positive regulation of trophoblast cell migration
negative regulation of double-strand break repair via homologous recombination
positive regulation of dendritic cell chemotaxis
double-strand break repair via homologous recombination
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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