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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: PGLQCHPPKD DEAPLRALLL GRGRCLPARA PAVAEENPKE SKPQAGTARP QDVNRRDQQR NPGTSTTPSQ PNSAGVQDTE MGPCRRHLDS VLQQLQTEVY RGAQTLYVPN CDHRGFYRKR QCRSSQGQRR GPCWC
Highest antigen sequence identity to the following orthologs: Mouse - 71%, Rat - 68%.
IGF-BPs control the distribution, function and activity of IGFs in various cell tissues and body fluids. IGF-BP6, which specifically inhibits IGF-II actions, is produced by bone cells and is the major IGF-BP present in cerebrospinal fluid. IGF-BP6 has been shown to inhibit IGF-II-dependent cancers such as neuroblastoma, colon cancer and rhabdomyosarcoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: IBP-6; IGF binding protein 6; IGFBP; IGFBP-6; IGFBP6; Insulin like growth factor binding protein; unnamed protein product
Gene Aliases: IBP6
UniProt ID: (Human) P24592
Entrez Gene ID: (Human) 3489
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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