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Invitrogen

Phospho-FOXO3A (Ser315) Polyclonal Antibody

1 Published Figure
1 Reference
View all (69) FOXO3A antibodies

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Phospho-FOXO3A (Ser315) Polyclonal Antibody

Product Details

PA5-64553

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:1,000
View 1 publication 1 publication
Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human FKHRL1 (Phospho-Ser315)
3D Epitope / Immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Amount

100 µg

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 0.87% NaCl, 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2665187

Product Specific Information

Phospho-FOXO3 (Ser315) Polyclonal Antibody detects endogenous levels of FOXO3 only when phosphorylated at Ser315.

Target Information

USP48 is a protein containing domains that associate it with the peptidase family C19, also known as family 2 of ubiquitin carboxyl-terminal hydrolases. Family members function as deubiquitinating enzymes, recognizing and hydrolyzing the peptide bond at the C-terminal glycine of ubiquitin. Enzymes in peptidase family C19 are involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: forkhead box O3A; forkhead homolog (rhabdomyosarcoma) like 1; forkhead in rhabdomyosarcoma-like 1; forkhead protein FKHR2; forkhead, Drosophila, homolog of, in rhabdomyosarcoma-like 1; FOXO3A-; member of FKHR-subclass forkhead/winged helix family; unnamed protein product

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Gene Aliases: 1110048B16Rik; 2010203A17Rik; AF6q21; Fkhr2; FKHRL1; FKHRL1P2; FOXO2; FOXO3A

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UniProt ID: (Human) O43524, (Mouse) Q9WVH4

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Entrez Gene ID: (Human) 2309, (Mouse) 56484, (Rat) 294515

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Function(s)
transcription regulatory region sequence-specific DNA binding RNA polymerase II core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding transcription cofactor binding transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding DNA binding transcription factor activity, sequence-specific DNA binding protein binding beta-catenin binding protein kinase binding chromatin DNA binding mitochondrial RNA polymerase binding promoter specificity activity sequence-specific DNA binding sequence-specific double-stranded DNA binding
Process(es)
negative regulation of transcription from RNA polymerase II promoter ovulation from ovarian follicle initiation of primordial ovarian follicle growth antral ovarian follicle growth oocyte maturation regulation of transcription, DNA-templated regulation of transcription from RNA polymerase II promoter transcription from mitochondrial promoter regulation of translation phagocytosis response to xenobiotic stimulus gene expression positive regulation of autophagy positive regulation of muscle atrophy DNA damage response, signal transduction by p53 class mediator negative regulation of cell migration response to nutrient levels tumor necrosis factor-mediated signaling pathway cellular response to oxidative stress cellular response to glucose starvation glucose homeostasis response to starvation positive regulation of apoptotic process positive regulation of neuron apoptotic process positive regulation of regulatory T cell differentiation positive regulation of erythrocyte differentiation negative regulation of neuron differentiation positive regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter brain morphogenesis response to fatty acid cellular response to glucose stimulus cellular response to corticosterone stimulus response to dexamethasone negative regulation of canonical Wnt signaling pathway neuronal stem cell population maintenance extrinsic apoptotic signaling pathway in absence of ligand positive regulation of hydrogen peroxide-mediated programmed cell death positive regulation of pri-miRNA transcription from RNA polymerase II promoter positive regulation of reactive oxygen species biosynthetic process cellular response to beta-amyloid cellular response to nerve growth factor stimulus response to water-immersion restraint stress regulation of neural precursor cell proliferation positive regulation of endothelial cell apoptotic process regulation of reactive oxygen species metabolic process
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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