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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Predicted to react with Human samples.
Tumor necrosis factor, α-induced protein 8-like 1, also known as TNFα-IP 8L1, is a 186 amino acid protein belonging to the TNFα-IP 8 family. Members of the TNFα-IP 8 family are induced by nuclear factor-κB 9 (NFκB) and tumor necrosis factor (TNF), although induction by TNF is dependent upon NFκB activation. TNFα-IP 8 proteins also act as a negative mediator of apoptosis and may play a role in tumor progression. They suppress TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: oxidative stress regulated gene-beta; oxidative stress-regulated gene-beta; oxy-beta; TNF alpha-induced protein 8-like protein 1; TNFAIP8-like protein 1; tumor necrosis factor, alpha induced protein 8 like 1; tumor necrosis factor, alpha-induced protein 8-like protein 1; unnamed protein product
Gene Aliases: 2600017J23Rik; TIPE1; TNFAIP8L1
UniProt ID: (Human) Q8WVP5, (Mouse) Q8K288
Entrez Gene ID: (Human) 126282, (Mouse) 66443
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