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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Predicted to react with Mouse and Rat samples.
The DYNLRB1 gene is a member of the roadblock dynein light chain family. The encoded cytoplasmic protein is capable of binding intermediate chain proteins, interacts with transforming growth factor-beta, and has been implicated in the regulation of actin modulating proteins. Upregulation of this gene has been associated with hepatocellular carcinomas, suggesting that this gene may be involved in tumor progression. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene have been defined on chromosomes 12 and 18.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: bithoraxoid-like protein; BLP; dynein light chain 2A, cytoplasmic; dynein, cytoplasmic, light chain 2A; dynein, cytoplasmic, light polypeptide 2A; dynein-associated protein Km23; dynein-associated protein RKM23; roadblock domain-containing protein 1; ROBL/LC7-like 1; robl/LC7-like protein; unnamed protein product
Gene Aliases: 2010012N15Rik; 2010320M17Rik; 9430076K19Rik; BITH; BLP; DNCL2A; DNLC2A; km23; km23-1; ROBLD1
UniProt ID: (Human) Q9NP97, (Mouse) P62627, (Rat) P62628
Entrez Gene ID: (Human) 83658, (Mouse) 67068, (Rat) 170714
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