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Invitrogen
Chordin Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-68471
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthesized peptide derived from human Chordin [aa 905-954].
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol, 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Predicted to react with Mouse and Rat samples.
Target Information
This gene encodes a secreted protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta-like bone morphogenetic proteins and sequestering them in latent complexes. The encoded protein may also have roles in organogenesis and during adulthood. Multiple transcript variants encoding distinct isoforms have been identified for this gene. Other alternative splice variants have been described but their full length sequence has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Chd; secreted protein; putative secreted antagonist of transforming growth factor beta-like morphogens; unnamed protein product
Gene Aliases: Chd
UniProt ID: (Human) Q9H2X0, (Mouse) Q9Z0E2
Entrez Gene ID: (Human) 8646, (Rat) 117275, (Mouse) 12667
embryonic axis specification
skeletal system development
osteoblast differentiation
in utero embryonic development
gastrulation with mouth forming second
mesoderm formation
positive regulation of mesenchymal cell proliferation
smoothened signaling pathway
pattern specification process
central nervous system development
cell proliferation
visual learning
fibroblast growth factor receptor signaling pathway
dorsal/ventral pattern formation
gene expression
neural crest formation
mesenchymal cell fate commitment
protein import
spinal cord dorsal/ventral patterning
negative regulation of cell migration
BMP signaling pathway
negative regulation of BMP signaling pathway
forebrain development
embryonic heart tube development
exploration behavior
descending aorta development
maintenance of protein location
negative regulation of osteoblast differentiation
positive regulation of cell adhesion
regulation of neuronal synaptic plasticity
neuron fate commitment
system development
artery morphogenesis
venous blood vessel morphogenesis
synapse organization
long-term synaptic potentiation
epithelial cell fate commitment
presynaptic modulation of chemical synaptic transmission
chordate pharynx development
cranial skeletal system development
short-term synaptic potentiation
floor plate development
specification of segmental identity, mandibular segment
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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