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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
This target displays homology in the following species: Dog: 93%; Horse: 86%; Human: 100%; Pig: 79%; Rabbit: 79%; Rat: 79%
This gene encodes a WD repeat protein, which interacts with Cockayne syndrome type B (CSB) protein and with p44 protein, a subunit of the RNA polymerase II transcription factor IIH. Mutations in this gene have been identified in patients with hereditary disease Cockayne syndrome (CS). CS cells are abnormally sensitive to ultraviolet radiation and are defective in the repair of transcriptionally active genes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Cockayne syndrome WD repeat protein CSA; DNA excision repair protein ERCC-8
Gene Aliases: CKN1; CSA; ERCC8
Entrez Gene ID: (Human) 1161
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