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Invitrogen
FIP200 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-71583
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide between 489-515 amino acids from the Central region of human RB1CC1
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.34 mg/mL
Amount
136 µg
Purification
Protein A, Antigen affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
The protein encoded by this gene interacts with signaling pathways to coordinately regulate cell growth, cell proliferation, apoptosis, autophagy, and cell migration. This tumor suppressor also enhances retinoblastoma 1 gene expression in cancer cells. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 200 kDa FAK family kinase-interacting protein; CC1; coiled-coil-forming protein 1; FAK family kinase-interacting protein of 200 kDa; KIAA0203; phosphatase 1, regulatory subunit 131; unnamed protein product
Gene Aliases: 2900055E04Rik; 5930404L04Rik; ATG17; CC1; FIP200; LaXp180; PPP1R131
UniProt ID: (Human) Q8TDY2, (Mouse) Q9ESK9
Entrez Gene ID: (Human) 9821, (Mouse) 12421
autophagosome assembly
mitophagy
pexophagy
liver development
positive regulation of protein phosphorylation
autophagy
heart development
negative regulation of cell proliferation
positive regulation of autophagy
ribophagy
piecemeal microautophagy of nucleus
negative regulation of apoptotic process
innate immune response
positive regulation of cell size
positive regulation of JNK cascade
defense response to virus
reticulophagy
glycophagy
regulation of protein lipidation
negative regulation of extrinsic apoptotic signaling pathway
macroautophagy
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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