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Invitrogen
MYO18A Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-76549
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein of human MYO18A.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Target Information
MYO18A may link Golgi membranes to the cytoskeleton and participate in the tensile force required for vesicle budding from the Golgi. Thereby, may play a role in Golgi membrane trafficking and could indirectly give its flattened shape to the Golgi apparatus. Alternatively, in concert with LURAP1 and CDC42BPA/CDC42BPB, has been involved in modulating lamellar actomyosin retrograde flow that is crucial to cell protrusion and migration. May be involved in the maintenance of the stromal cell architectures required for cell to cell contact. Regulates trafficking, expression, and activation of innate immune receptors on macrophages. Plays a role to suppress inflammatory responsiveness of macrophages via a mechanism that modulates CD14 trafficking.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 12 kDa TGF-beta-1-induced antiapoptotic factor; basic salivary proline-rich protein 1-like; basic salivary proline-rich protein 2-like; KIAA0216; molecule associated with Jak-3 N-terminal; molecule associated with JAK3 N-terminus; myosin 18A; myosin containing a PDZ domain; myosin containing PDZ domain; myosin XVIIIb; myosin; SP-R210aS; SP-A receptor SP-R210 short isoform; MyoXVIIIA; MsSP-R210aCL; SP-A receptor SP-R210 isoform; MyoXVIIIA; MsSP-R210aCS; SP-A receptor SP-R210 isoform; Putative TGFB1-induced anti-apoptotic factor 1; SP-A receptor subunit SP-R210 alphaS; surfactant protein receptor SP-R210; TGF-beta-1-induced antiapoptotic factor 1; TGFB1-induced anti-apoptotic factor 1; unconventional myosin-XVIIIA isoform 6 cardiac; unnamed protein product
Gene Aliases: MAJN; MyoPDZ; MYSPDZ; SP-R210; SPR210; TIAF1
UniProt ID: (Human) Q92614, (Mouse) Q9JMH9
Entrez Gene ID: (Human) 399687, (Rat) 360570, (Mouse) 360013
Golgi organization
I-kappaB kinase/NF-kappaB signaling
cell migration
actomyosin structure organization
regulation of macrophage activation
negative regulation of apoptotic process
Golgi vesicle budding
positive regulation of protein secretion
cellular response to interferon-gamma
Golgi ribbon formation
asymmetric Golgi ribbon formation
positive regulation of opsonization
DNA metabolic process
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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