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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
The protein encoded by this gene is part of a protein complex required for the retrotranslocation or dislocation of misfolded proteins from the endoplasmic reticulum lumen to the cytosol, where they are degraded by the proteasome in a ubiquitin-dependent manner. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: IBD2; sel-1 suppressor of lin-12-like; sel-1 suppressor of lin-12-like 1; sel-1L; Sel1 (suppressor of lin-12) 1 homolog; SEL1L adaptor subunit of ERAD E3 ubiquitin ligase; SEL1L ERAD E3 ligase adaptor subunit; SEL1L, ERAD E3 ligase adaptor subunit; similar to Caenorhabditis elegans sel-1 protein; similar to Caenorhabditis elegans SEL-1, negative regulator of Notch; Suppressor of lin 12 (sel-1), C. elegans, homolog of; suppressor of lin-12-like protein 1; TSA305; unnamed protein product
Gene Aliases: Hrd3; mKIAA4137; NEDGSAF; NEDHGFA; PRO1063; SEL1-LIKE; Sel1h; SEL1L1
UniProt ID: (Human) Q9UBV2, (Mouse) Q9Z2G6
Entrez Gene ID: (Human) 6400, (Mouse) 20338, (Rat) 314352
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