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Invitrogen
Adenosine Deaminase Polyclonal Antibody
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FIGURE: 1 / 4
Adenosine Deaminase Antibody (PA5-78722) in IHC (P)
Immunohistochemistry analysis of ADA on paraffin-embedded mouse intestine tissue. Antigen retrieval was performed using citrate buffer (pH6, epitope retrieval solution) for 20 mins. Sample was blocked using 10% goat serum, incubated with ADA polyclonal antibody (Product# PA5-78722) with a dilution of 1 µg/mL (overnight at 4°C), and followed by biotinylated goat anti-rabbit IgG (30 minutes at 37°C). Developm... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-78722
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
E. coli-derived rat ADA recombinant protein (Position: A2-H241).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Lyophilized
Concentration
500 µg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS with 4mg trehalose
Contains
0.05mg sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: rat brain tissue, rat liver tissue, rat liver tissue, mouse liver tissue, mouse spleen tissue, mouse NIH/3T3 whole cell. IHC: rat spleen tissue, mouse intestine tissue, rat brain tissue.
Target Information
Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine. Plays an important role in purine metabolism and in adenosine homeostasis. Modulates signaling by extracellular adenosine, and so contributes indirectly to cellular signaling events. May act as a positive regulator of T-cell coactivation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Ada; adenosine aminohydrolase; adenosine deaminase (EC 3.5.4.4); RP11-61L14.5; unnamed protein product
UniProt ID: (Rat) Q920P6, (Mouse) P03958
Entrez Gene ID: (Rat) 24165, (Mouse) 11486
response to hypoxia
in utero embryonic development
histamine secretion
trophectodermal cell differentiation
liver development
placenta development
germinal center B cell differentiation
positive regulation of germinal center formation
negative regulation of leukocyte migration
negative regulation of mature B cell apoptotic process
adenosine catabolic process
deoxyadenosine catabolic process
AMP catabolic process
purine ribonucleoside monophosphate biosynthetic process
response to xenobiotic stimulus
positive regulation of heart rate
response to purine-containing compound
lung development
positive regulation of B cell proliferation
purine nucleotide salvage
GMP salvage
regulation of T cell differentiation in thymus
positive regulation of T cell differentiation in thymus
response to vitamin E
regulation of cell-cell adhesion mediated by integrin
T cell activation
negative regulation of circadian sleep/wake cycle, non-REM sleep
response to hydrogen peroxide
negative regulation of apoptotic process
hypoxanthine salvage
AMP salvage
regulation of circadian sleep/wake cycle, sleep
regulation of T cell differentiation
positive regulation of T cell differentiation
positive regulation of smooth muscle contraction
dAMP catabolic process
dATP catabolic process
adenosine metabolic process
hypoxanthine biosynthetic process
inosine biosynthetic process
xanthine biosynthetic process
positive regulation of alpha-beta T cell differentiation
response to cadmium ion
lung alveolus development
Peyer's patch development
embryonic digestive tract development
negative regulation of inflammatory response
positive regulation of calcium-mediated signaling
positive regulation of T cell receptor signaling pathway
positive regulation of T cell activation
negative regulation of adenosine receptor signaling pathway
negative regulation of penile erection
negative regulation of thymocyte apoptotic process
negative regulation of mucus secretion
response to L-arginine
IMP salvage
inhibition of non-skeletal tissue mineralization
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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