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Invitrogen
Cystatin C Polyclonal Antibody
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FIGURE: 1 / 2
Cystatin C Antibody (PA5-79078) in IHC (P)
Immunohistochemistry analysis of Cystatin C on paraffin-embedded mouse brain tissue. Antigen retrieval was performed using citrate buffer (pH6, epitope retrieval solution) for 20 mins. Sample was blocked using 10% goat serum, incubated with Cystatin C polyclonal antibody (Product# PA5-79078) with a dilution of 1 µg/mL (overnight at 4°C), and followed by biotinylated goat anti-rabbit IgG (30 minutes at 37°C)... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-79078
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
E. coli-derived human Cystatin C recombinant protein (Position: K31-A146).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Lyophilized
Concentration
500 µg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS with 4mg trehalose
Contains
0.05mg sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: human COLO-320 whole cell, human placenta tissue, human HepG2 whole cell, mouse brain tissue. IHC: mouse brain tissue.
Target Information
Cystatin C, a member of the type 2 cystatin superfamily, is a potent inhibitor of cysteine proteinases, both endogenous (lysosomal cathepsins), and pathogenic. Cystatin C is a 13 kDa secreted protein which is found in high concentrations in biological fluids and is thought to be expressed by all human nucleated cells. Changes in Cystatin C have been documented in a number of cardiovascular diseases, including atherosclerosis, amyloid angiopathy and myocardial infarction. Its low molecular weight also means that Cystatin C can be used as a marker of renal failure.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: AD8; bA218C14.4 (cystatin C); CST3; cystatin 3; cystatin-3; Cystatin3; CystatinC; epididymis secretory protein Li 2; gamma-trace; MGC117328; neuroendocrine basic polypeptide; OTTHUMP00000030440; OTTHUMP00000164181; OTTHUMP00000164182; OTTMUSP00000016736; post-gamma-globulin; RP23-250M11.9; unnamed protein product
Gene Aliases: ADLDWA; ARMD11; CysC; HEL-S-2
UniProt ID: (Human) P01034, (Mouse) P21460
Entrez Gene ID: (Human) 1471, (Mouse) 13010
eye development
response to hypoxia
defense response
salivary gland development
embryo implantation
positive regulation of cell proliferation
male gonad development
response to xenobiotic stimulus
response to toxic substance
response to carbohydrate
negative regulation of collagen catabolic process
negative regulation of extracellular matrix disassembly
response to nutrient levels
response to estradiol
regulation of tissue remodeling
cellular response to oxidative stress
positive regulation of DNA replication
negative regulation of proteolysis
response to axon injury
Sertoli cell development
negative regulation of elastin catabolic process
negative regulation of blood vessel remodeling
cellular response to hydrogen peroxide
fibril organization
immune response
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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