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Invitrogen
PLK2 Polyclonal Antibody
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FIGURE: 1 / 9
PLK2 Antibody (PA5-79832) in ICC/IF
Immunocytochemistry analysis of PLK2 using anti-PLK2 antibody (Product # PA5-79832). PLK2 was detected in a section of A549 cell. Enzyme antigen retrieval was performed using IHC enzyme antigen retrieval reagent for 15 mins. The cells were blocked with 10% goat serum and then incubated with 1μg/mL rabbit anti-PLK2 antibody (Product # PA5-79832) overnight at 4°C. Biotinylated goat anti-rabbit IgG was used as secondary antibody and incubated for 30 minutes at 37°C. The section was developed using Strepavidin-Biotin-Complex (SABC) with DAB as... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-79832
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human PLK2 (666-685aa SSELKNRMEYALNMLLQRCN).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Lyophilized
Concentration
500 µg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5mg BSA
Contains
0.05mg sodium azide, 0.05mg thimerosal
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: A431 Cell, 293T Cell, COLO-320 Cell. IHC: human lung cancer tissue, rat intestine tissue, rat brain tissue. ICC/IF: A549 cell. Flow: A549 cell.
Target Information
PLK2 is a serum inducible serine/threonine kinase that is a member of the polo family of serine/threonine kinases which have a role in normal cell division. The kinase may play a role in embryogenesis, wound healing, and neoplasia.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: h PLK-2; PLK-2; polo-like kinase 1; serine/threonine kinase; serine/threonine-protein kinase SNK; serum-inducible kinase; SNK; unnamed protein product
Gene Aliases: hPlk2; hSNK; SNK
UniProt ID: (Human) Q9NYY3, (Rat) Q9R012, (Mouse) P53351
Entrez Gene ID: (Human) 10769, (Rat) 83722, (Mouse) 20620
G1/S transition of mitotic cell cycle
negative regulation of inflammatory response to antigenic stimulus
protein phosphorylation
mitotic spindle organization
Ras protein signal transduction
memory
positive regulation of autophagy
regulation of cell cycle process
negative regulation of angiogenesis
DNA damage response, signal transduction by p53 class mediator
Rap protein signal transduction
negative regulation of apoptotic process
positive regulation of I-kappaB kinase/NF-kappaB signaling
positive regulation of protein catabolic process
regulation of centriole replication
regulation of synaptic plasticity
long-term synaptic potentiation
long term synaptic depression
negative regulation of apoptotic process in bone marrow
positive regulation of cell migration involved in sprouting angiogenesis
negative regulation of cellular senescence
mitotic cell cycle
positive regulation of receptor internalization
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
negative regulation of dendritic spine development
negative regulation of excitatory postsynaptic potential
regulation protein catabolic process at postsynapse
negative regulation of protein localization to cell surface
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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