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Invitrogen
RRM2 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-79937
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence at the N-terminus of human RRM2 (1-33aa MLSLRVPLAPITDPQQLQLSPLKGLSLVDKENT).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Lyophilized
Concentration
500 µg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5mg BSA
Contains
0.05mg sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: Rat Cardiac Muscle Tissue, Mouse Cardiac Muscle Tissue, A431 whole cell, HELA whole cell. IHC: human mammary cancer tissue.
Target Information
RRM2 is one of two non-identical subunits for ribonucleotide reductase. This reductase catalyzes the formation of deoxyribonucleotides from ribonucleotides. Synthesis of the protein (M2) is regulated in a cell-cycle dependent fashion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: ribonucleoside-diphosphate reductase M2 chain; Ribonucleotide reductase 2; ribonucleotide reductase M2 polypeptide; ribonucleotide reductase small chain; ribonucleotide reductase small subunit; ribonucleotide reductase subunit M2; RRR2M; uncharacterized protein C2orf48; unnamed protein product
Gene Aliases: C2orf48; R2; RR2; RR2M
UniProt ID: (Human) P31350, (Rat) Q4KLN6, (Mouse) P11157
Entrez Gene ID: (Human) 6241, (Rat) 362720, (Mouse) 20135
pyrimidine nucleobase metabolic process
dTMP biosynthetic process
DNA repair
positive regulation of cell proliferation
ribonucleoside diphosphate metabolic process
deoxyribonucleotide metabolic process
deoxyribonucleotide biosynthetic process
2'-deoxyribonucleotide biosynthetic process
protein heterotetramerization
nucleobase-containing small molecule metabolic process
positive regulation of G1/S transition of mitotic cell cycle
positive regulation of mitotic cell cycle phase transition
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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