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Invitrogen
PRDM9 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-84424
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human PRDM9. Recombinant protein control fragment (Product #RP-101424).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.05 mg/mL
Amount
5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: QELGIKWGSK WKKELMAGRE PKPEIHPCPS CCLAFSSQKF LSQHVERNHS SQNFPGPSAR KLLQPENPCP G
Highest antigen sequence indentity to the following orthologs: Mouse - 63%, Rat - 66%.
Target Information
The PR domain is a protein-protein interaction module of about 100 amino acids. PR domain-containing proteins, such as PRDM9, are often involved in transcriptional regulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: [histone H3]-lysine36 N-trimethyltransferase PRDM9; [histone H3]-lysine4 N-trimethyltransferase PRDM9; [histone H3]-lysine9 N-trimethyltransferase PRDM9; [histone H4]-lysine20 N-methyltransferase PRDM9; [histone H4]-N-methyl-L-lysine20 N-methyltransferase PRDM9; histone methyl transferase; minisatellite binding protein 3 (115kD); PFM6; PR domain 9; PR domain containing 9; PR domain zinc finger protein 9; protein-lysine N-methyltransferase PRDM9; unnamed protein product
Gene Aliases: KMT8B; MEISETZ; MSBP3; PFM6; ZNF899
UniProt ID: (Human) Q9NQV7
Entrez Gene ID: (Human) 56979
transcription regulatory region sequence-specific DNA binding
zinc ion binding
recombination hotspot binding
protein-lysine N-methyltransferase activity
histone methyltransferase activity
histone methyltransferase activity (H3-K4 specific)
protein homodimerization activity
sequence-specific DNA binding
histone methyltransferase activity (H3-K36 specific)
histone H4K20me methyltransferase activity
histone H4K20 monomethyltransferase activity
histone H3K9 trimethyltransferase activity
histone H3K36 trimethyltransferase activity
histone H3K4 trimethyltransferase activity
meiotic gene conversion
chromatin remodeling
regulation of transcription, DNA-templated
synapsis
female gamete generation
regulation of gene expression
positive regulation of reciprocal meiotic recombination
reciprocal DNA recombination
negative regulation of apoptotic process
male gamete generation
meiosis I cell cycle process
positive regulation of fertilization
double-strand break repair involved in meiotic recombination
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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