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Invitrogen
Calcium Sensing Receptor Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-85137
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the Extracellular domain of human Calcium Sensing Receptor. The exact sequence is proprietary.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.55 mg/mL
Amount
55 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 20% glycerol
Contains
0.025% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Keep as concentrated solution.
Predicted reactivity: Mouse (93%), Rat (94%), Dog (95%), Cat (95%), Pig (95%), Bovine (95%).
Positive Control: 293T, A431, H1299, HeLa, mouse brain, mouse placenta.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Senses changes in the extracellular concentration of calcium ions. The activity of this receptor is mediated by a G- protein that activates a phosphatidylinositol-calcium second messenger system.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Ca sensing receptor; calcium receptor|CaR; Calcium-sensing receptor (hypocalciuric hypercalcemia 1, severe neonatal hyperparathyroidism); CaSR antibody; cation sensing receptor; extracellular domain; G protein-coupled membrane receptor; G protein-coupled receptor, family C, group 2, member A; G-protein coupled receptor; parathyroid Ca(2+)-sensing receptor 1; parathyroid Cell calcium-sensing receptor; parathyroid cell calcium-sensing receptor 1; PCaR1; unnamed protein product
Gene Aliases: CAR; EIG8; FHH; FIH; GPRC2A; hCasR; HHC; HHC1; HYPOC1; NSHPT; PCAR1; RaKCaR
UniProt ID: (Human) P41180, (Mouse) Q9QY96, (Rat) P48442
Entrez Gene ID: (Human) 846, (Mouse) 12374, (Rat) 24247
ossification
response to ischemia
detection of calcium ion
cellular calcium ion homeostasis
G-protein coupled receptor signaling pathway
adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
phospholipase C-activating G-protein coupled receptor signaling pathway
JNK cascade
chemosensory behavior
positive regulation of cell proliferation
anatomical structure morphogenesis
response to metal ion
positive regulation of insulin secretion
bile acid secretion
cellular response to hepatocyte growth factor stimulus
vasodilation
positive regulation of vasoconstriction
branching morphogenesis of an epithelial tube
positive regulation of positive chemotaxis
response to calcium ion
regulation of calcium ion transport
fat pad development
positive regulation of ERK1 and ERK2 cascade
cellular response to vitamin D
cellular response to glucose stimulus
cellular response to low-density lipoprotein particle stimulus
cellular response to hypoxia
response to fibroblast growth factor
positive regulation of calcium ion import
regulation of presynaptic membrane potential
positive regulation of NLRP3 inflammasome complex assembly
cellular response to peptide
chloride transmembrane transport
positive regulation of intracellular signal transduction
positive regulation of gene expression
positive regulation of ATPase activity
adenylate cyclase-activating G protein-coupled cAMP receptor signaling pathway
detection of chemical stimulus
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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