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Invitrogen
IFNGR1 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-86322
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide, corresponding to amino acids 430-480 of Human IFN-gammaRalpha.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Purity is > 95% by SDS-PAGE.
Target Information
This gene (IFNGR1) encodes the ligand-binding chain (alpha) of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: antiviral protein, type 2; AVP, type 2; CD119 antigen; CDw119; cytokine receptor; IFN-gamma receptor 1; IFN-gamma-R-alpha; IFN-gamma-R1; IFNgR1; immune interferon receptor 1; INF-g receptor; interferon gamma receptor alpha-chain; interferon gamma receptor precursor; interferon-gamma receptor; interferon-gamma receptor alpha chain; interferon-gamma receptor precursor; unnamed protein product
Gene Aliases: CD119; Ifgr; IFN-gammaR; IFNGR; IMD27A; IMD27B; Nktar
UniProt ID: (Human) P15260, (Mouse) P15261
Entrez Gene ID: (Human) 3459, (Rat) 116465, (Mouse) 15979
microglial cell activation
immune system process
defense response
biological_process
response to virus
positive regulation of gene expression
cytokine-mediated signaling pathway
positive regulation of tumor necrosis factor production
type III interferon-mediated signaling pathway
astrocyte activation
defense response to virus
interferon-gamma-mediated signaling pathway
negative regulation of beta-amyloid clearance
positive regulation of beta-amyloid formation
signal transduction
cellular response to virus
JAK-STAT cascade
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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