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Invitrogen
SH3BP2 Polyclonal Antibody
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FIGURE: 1 / 1
SH3BP2 Antibody (PA5-87739) in WB
Western blot analysis of SH3BP2 in extracts of various cell lines. Samples were incubated with SH3BP2 Polyclonal antibody (Product # PA5-87739) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-87739
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 392-561 of human SH3BP2 (NP_0011161531)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
2.27 mg/mL
Amount
227 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: VPEAMARPAV LPRPEKPQLP HLQRSPPDGQ SFRSFSFEKP RQPSQADTGG DDSDEDYEKV PLPNSVFVNT TESCEVERLF KATSPRGEPQ DGLYCIRNSS TKSGKVLVVW DETSNKVRNY RIFEKDSKFY LEGEVLFVSV GSMVEHYHTH VLPSHQSLLL RHPYGYTGPR; Positive Samples: A549, Mouse spleen, Mouse lung
Target Information
The protein encoded by this gene has an N-terminal pleckstrin homology (PH) domain, an SH3-binding proline-rich region, and a C-terminal SH2 domain. The protein binds to the SH3 domains of several proteins including the ABL1 and SYK protein tyrosine kinases, and functions as a cytoplasmic adaptor protein to positively regulate transcriptional activity in T, natural killer (NK), and basophilic cells. Mutations in this gene result in cherubism. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FLJ42079; SH3 domain-binding protein 2
Gene Aliases: 3BP2
Entrez Gene ID: (Mouse) 24055
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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