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CPSF3 Polyclonal Antibody
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FIGURE: 1 / 1
CPSF3 Antibody (PA5-88501) in WB
Western blot analysis of CPSF3 in extracts of various cell lines. Samples were incubated with CPSF3 Polyclonal antibody (Product # PA5-88501) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-88501
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 435-684 of human CPSF3 (NP_0572911)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.1 mg/mL
Amount
10 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: YEDNDEVHIE VHNPRNTEAV TLNFRGEKLA KVMGFLADKK PEQGQRVSGI LVKRNFNYHI LSPCDLSNYT DLAMSTVKQT QAIPYTGPFN LLCYQLQKLT GDVEELEIQE KPALKVFKNI TVIQEPGMVV LEWLANPSND MYADTVTTVI LEVQSNPKIR KGAVQKVSKK LEMHVYSKRL EIMLQDIFGE DCVSVKDDSI LSVTVDGKTA NLNLETRTVE CEEGSEDDES LREMVELAAQ RLYEALTPVH; Positive Samples: Mouse liver, Mouse spleen; Cellular Location: Nucleus
Target Information
Most eukaryotic mRNA precursors (pre-mRNAs) undergo extensive maturational processing, including cleavage and polyadenylation at the 3-prime end. CPSF3 encodes the 73-kD subunit of the cleavage and polyadenylation specificity factor (CPSF) and is the pre-mRNA 3-prime-end-processing endonuclease (Mandel et al., 2006).
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: cleavage and polyadenylation specific factor 3, 73kDa; cleavage and polyadenylation specificity factor 73 kDa subunit; CPSF; CPSF 73 kDa subunit; mRNA 3'-end-processing endonuclease CPSF-73; unnamed protein product; YSH1
Gene Aliases: CPSF-73; CPSF73; NEDMHS; NEDMHSN
UniProt ID: (Human) Q9UKF6, (Mouse) Q9QXK7
Entrez Gene ID: (Human) 51692, (Mouse) 54451
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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