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Invitrogen
MRGPRX1 Polyclonal Antibody
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FIGURE: 1 / 4
MRGPRX1 Antibody (PA5-89019) in WB
Western blot analysis of MRGPRX1 in extracts of various cell lines. Samples were incubated with MRGPRX1 Polyclonal antibody (Product # PA5-89019) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-89019
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 263-322 of human MRGPRX1 (NP_6717323)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
2.24 mg/mL
Amount
224 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: LNSSANPIIY FFVGSFRQRQ NRQNLKLVLQ RALQDASEVD EGGGQLPEEI LELSGSRLEQ; Positive Samples: Mouse liver, Rat liver; Cellular Location: Cell membrane, Multi-pass membrane protein
Target Information
MRGX1 is an opiod receptor that has been reported exclusively in dorsal root ganglion. ESTs for MRGX1 have been identified in a human brain (hypothalamus) library and in a human cancer library.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: G protein-coupled receptor MRGX1; G protein-coupled receptor SNSR; G protein-coupled receptor SNSR3; MAS related GPR family member X4; Mas-related G protein-coupled receptor G2; mas-related G-protein coupled receptor member C11; mas-related G-protein coupled receptor member X1; MAS-related G-protein coupled receptor, member C; MAS-related gene C; MAS-related GPR, member C11; MAS-related GPR, member X1; MAS-related GPR, member X4; sensory neuron-specific G-protein coupled receptor 1; sensory neuron-specific G-protein coupled receptor 3/4; Sensory neuron-specific receptor
Gene Aliases: GPCR; MGRG2; MrgC; MrgC11; Mrgprc; Mrgprc11; Mrgprx4; MRGX1; Snsr; Snsr1; SNSR4
UniProt ID: (Human) Q96LB2, (Mouse) Q8CIP3, (Rat) Q8R4G1
Entrez Gene ID: (Human) 259249, (Mouse) 404242, (Rat) 282547
hematopoietic progenitor cell differentiation
signal transduction
G-protein coupled receptor signaling pathway
adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
phospholipase C-activating G-protein coupled receptor signaling pathway
chemosensory behavior
cell migration
cell surface bile acid receptor signaling pathway
chemokine-mediated signaling pathway
sneeze reflex
sensory perception of itch
negative regulation of sensory perception of pain
cell surface receptor signaling pathway
response to chloroquine
adenylate cyclase-modulating G-protein coupled receptor signaling pathway
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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