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Invitrogen
SLC7A1 Polyclonal Antibody
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FIGURE: 1 / 3
SLC7A1 Antibody (PA5-90039) in IHC (P)
Immunohistochemistry analysis of SLC7A1 in paraffin-embedded mouse brain. Samples were incubated with SLC7A1 Polyclonal antibody (Product # PA5-90039) using a dilution of 1:100 (40x lens). Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-90039
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1.42 mg/mL
Amount
142 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.09% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Positive Samples: Raji, Jurkat, 22RV1, Mouse testis, Rat brain, Rat liver; Cellular Location: Cell membrane, Multi-pass membrane protein
Immunogen sequence: SLDADQARTP DGNLDQ
Target Information
SLC7A1 is a high-affinity, low capacity permease involved in the transport of the cationic amino acids (arginine, lysine and ornithine) in non-hepatic tissues. It may also function as an ecotropic retroviral leukemia receptor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: amino acid transporter, cationic 1; CAT1; cationic amino acid transporter 1; cationic amino acid transporter y+ system; cationic amino acid transporter, y+ system; cationinc amino acid transporter 1; ecotropic retroviral leukemia receptor; ecotropic retroviral leukemia receptor homolog; ecotropic retroviral receptor; ecotropic retrovirus receptor; ecotropic retrovirus receptor homolog; REC1L; solute carrier family 7 (cationic amino acid transporter, y+ system), member 1; solute carrier family 7 member 1; Solute carrier family 7 member A1 (amino acid transporter cationic 1); system Y+ basic amino acid transporter; transport system y+; unnamed protein product
Gene Aliases: 4831426K01Rik; Atrc-1; ATRC1; CAT-1; CAT1; EcoR; ERR; HCAT1; mCAT-1; Rec-1; REC1L; Rev-1
UniProt ID: (Human) P30825, (Mouse) Q09143
Entrez Gene ID: (Human) 6541, (Rat) 25648, (Mouse) 11987
L-ornithine transmembrane transporter activity
virus receptor activity
L-histidine transmembrane transporter activity
protein binding
amino acid transmembrane transporter activity
basic amino acid transmembrane transporter activity
L-lysine transmembrane transporter activity
transmembrane transporter activity
L-arginine transmembrane transporter activity
amino acid transport
L-amino acid transport
lysine transport
ornithine transport
positive regulation of T cell proliferation
viral entry into host cell
transmembrane transport
amino acid import across plasma membrane
L-arginine import across plasma membrane
cation transmembrane transport
transport across blood-brain barrier
L-ornithine transmembrane transport
L-lysine transmembrane transport
L-histidine import across plasma membrane
arginine transmembrane transport
basic amino acid transport
regulation of TOR signaling
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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