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Invitrogen
AVIL Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-90703
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein (or fragment)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
2.23 mg/mL
Amount
223 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Positive Samples: HT-29, Mouse uterus, Mouse brain, Rat uterus, Rat testis, Rat brain; Cellular Location: Cell projection, Cytoplasm, axon, cytoskeleton
Target Information
AVIL is a member of the gelsolin/villin family of actin regulatory proteins. This protein has structural similarity to villin. It binds actin and may play a role in the development of neuronal cells that form ganglia.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: actin-binding protein DOC6; member of gelsolin actin-binding family; p92; peripheral nervous system villin-like protein; pervin; similar to villin and gelsolin; unnamed protein product; villin-like gelsolin family member
Gene Aliases: ADVIL; DOC6; NPHS21; p92
UniProt ID: (Human) O75366, (Rat) Q9WU06, (Mouse) O88398
Entrez Gene ID: (Human) 10677, (Rat) 79253, (Mouse) 11567
cytoskeleton organization
actin filament organization
nervous system development
actin polymerization or depolymerization
positive regulation of lamellipodium assembly
positive regulation of neuron projection development
actin filament severing
barbed-end actin filament capping
cilium morphogenesis
regulation of plasma membrane bounded cell projection organization
regulation of diacylglycerol biosynthetic process
positive regulation of cellular component biogenesis
positive regulation of lamellipodium organization
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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