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Invitrogen
Flotillin 1 Polyclonal Antibody
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FIGURE: 1 / 6
Flotillin 1 Antibody (PA5-95112) in IHC (P)
Immunohistochemistry (Paraffin) analysis of Flotillin 1 in paraffin-embedded section of human stomach camcer tissue using Flotillin 1 Polyclonal Antibody (Product # PA5-95112). Heat mediated antigen retrieval was performed in EDTA buffer (pH 8.0, epitope retrieval solution). The tissue section was blocked with 10% goat serum. The tissue section was then incubated with the primary antibody at a 2 µg/mL dilut... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-95112
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence in the middle region of human Flotillin 1 (219-234aa KKAAYDIEVNTRRAQA).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Lyophilized
Concentration
500 µg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS with 4mg trehalose
Contains
no preservative
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: human A431 whole cell lysates, human U251 whole cell lysates, human PC-3 whole cell lysates, human Hacat whole cell lysates, rat brain tissue lysates, rat skin tissue lysates, mouse brain tissue lysates, mouse skin tissue lysates. IHC: human stomach camcer, mouse brain, rat brain IP: A431 cell.|Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Target Information
Caveolae are small domains on the inner cell membrane involved in vesicular trafficking and signal transduction. FLOT1 encodes a caveolae-associated, integral membrane protein. The function of flotillin 1 has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: caveolae-associated protein; DADB-118P11.2; FLOT1; integral membrane component of caveolae; OTTHUMP00000164855; REG-2; reggie-2; unnamed protein product
Gene Aliases: Rareg; reggie-2
UniProt ID: (Human) O75955, (Mouse) O08917, (Rat) Q9Z1E1
Entrez Gene ID: (Human) 10211, (Mouse) 14251, (Rat) 64665
regulation of receptor internalization
endocytosis
cell-cell junction assembly
axonogenesis
axon guidance
extracellular matrix disassembly
positive regulation of synaptic transmission, dopaminergic
adherens junction organization
regulation of Rho protein signal transduction
intracellular signal transduction
positive regulation of I-kappaB kinase/NF-kappaB signaling
cell-cell adhesion mediated by cadherin
plasma membrane raft assembly
positive regulation of endocytosis
regulation of neurotransmitter uptake
caveola assembly
protein localization to plasma membrane
plasma membrane raft organization
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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