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Invitrogen
Beta III Tubulin Polyclonal Antibody
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FIGURE: 1 / 5
Beta III Tubulin Antibody (PA5-95875) in IHC (P)
Immunohistochemistry (Immunofluorescence) analysis of Beta III Tubulin in mouse brain. Samples were incubated with Beta III Tubulin Polyclonal antibody (Product # PA5-95875) using a dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-95875
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein (or fragment)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
3.37 mg/mL
Amount
337 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Positive Samples: HeLa, 293T, MCF7, mouse brain, mouse testis, rat brain, rat testis
Immunogen sequence: SDLQLERISV YYNEASSHKY VPRAILVDLE PGTMDSVRSG AFGHLFRPDN FIFGQSGAGN NWAKGHYTEG AELVDSVLDV VRKECENCDC LQGFQLTHSL GGGTGSGMGT LLISKVREEY PDRIMNTFSV VPSPKVSDTV VEPYNATLSI HQLVENTDET YCIDNEALYD ICFRTLKLAT PTYGDLNHLV SATMSGVTTS LRFPGQLNAD LRKLAVNMVP F
Target Information
The betaIII-tubulin isoform is present dominantly in cells of neuronal origin and it is one of the earliest markers of neuronal differentiation. It is regarded as a specific probe for the cells of neuronal origin as well as for the tumours originating from these cells. The betaIII-tubulin is most abundant in cells of neuronal origin, but was also detected in Sertoli cells of the testis and transiently in non-neuronal embryonic tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: beta 3 tubulin; beta tubulin 3; betaIII-tubulin; class III beta-tubulin; MC1R; microtubule protein; Neuron specific beta III Tubulin; neuron-specific class III beta-tubulin; TUBB; tubulin beta; Tubulin beta-3; Tubulin beta-4; tubulin beta-4 chain; tubulin beta-III; tubulin, beta 3; unnamed protein product
Gene Aliases: 3200002H15Rik; beta-4; CDCBM; CDCBM1; CFEOM3; CFEOM3A; FEOM3; M(beta)3; M(beta)6; TUBB4
UniProt ID: (Human) Q13509, (Rat) Q4QRB4, (Mouse) Q9ERD7
Entrez Gene ID: (Human) 10381, (Rat) 246118, (Mouse) 22152
GTPase activity
structural constituent of cytoskeleton
protein binding
GTP binding
peptide binding
netrin receptor binding
double-stranded RNA binding
calcium ion binding
protein domain specific binding
ubiquitin protein ligase binding
GTPase activating protein binding
MHC class I protein binding
macromolecular complex binding
microtubule cytoskeleton organization
mitotic cell cycle
microtubule-based process
axon guidance
biological_process
neuron differentiation
sperm motility
negative regulation of microtubule polymerization
netrin-activated signaling pathway
regulation of synapse organization
spindle assembly
odontoblast differentiation
dorsal root ganglion development
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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