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Invitrogen
IL-11 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-95982
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein (or fragment).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol, 0.05% BSA
Contains
0.09% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Positive Samples: Human plasma
Target Information
Interleukins (ILs) are a large group of cytokines that are produced mainly by leukocytes, although some are produced by certain phagocytes and auxiliary cells. ILs have a variety of functions, but most function to direct other immune cells to divide and differentiate. Each IL acts on a specific, limited group of cells through a receptor specific for that IL.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: adipogenesis inhibitory factor; il 11; IL-11ra; IL10RA; IL11 inhibitor; ILN; Interleukin; Interleukin11; MGC2146; oprelvekin; unnamed protein product
Gene Aliases: AGIF; IL-11
UniProt ID: (Human) P20809, (Mouse) P47873
Entrez Gene ID: (Human) 3589, (Mouse) 16156, (Rat) 171040
positive regulation of cell proliferation
positive regulation of peptidyl-serine phosphorylation
interleukin-11-mediated signaling pathway
positive regulation of MAPK cascade
positive regulation of transcription from RNA polymerase II promoter
negative regulation of hormone secretion
positive regulation of peptidyl-tyrosine phosphorylation
regulation of complement-dependent cytotoxicity
negative regulation of endothelial cell apoptotic process
negative regulation of cytokine-mediated signaling pathway
B cell differentiation
megakaryocyte differentiation
fat cell differentiation
negative regulation of cytokine activity
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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