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Invitrogen
STOX1 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-98549
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human Storkhead-box protein 1 protein (559-858AA)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
4 mg/mL
Amount
100 µg
Purification
Protein G
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.03% ProClin 300
Storage conditions
-20°C or -80°C if preferred
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
STOX1 (Storkhead box 1), also known as PEE4 or C10orf24, is a winged-helix domain containing transcription factor believed to play a role in the differentiation of stem cells. As a DNA-binding protein, STOX1 exists as three alternatively spliced isoforms, designated A, B and C, all of which localize to either the cytoplasm or the nucleus. Defects in STOX1 are the cause of pre-eclampsia/eclampsia 4 (PEE4), also known as gestational proteinuric hypertension. STOX1 was also found to be functionally involved in late-onset Alzheimer's disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: PEE4; unnamed protein product; winged-helix domain-containing protein
Gene Aliases: C10orf24
UniProt ID: (Human) Q6ZVD7
Entrez Gene ID: (Human) 219736
regulation of transcription from RNA polymerase II promoter
regulation of mitotic cell cycle
regulation of gene expression
positive regulation of gene expression
negative regulation of gene expression
positive regulation of peptidyl-threonine phosphorylation
regulation of mitochondrion organization
positive regulation of G2/M transition of mitotic cell cycle
positive regulation of peptidyl-serine phosphorylation
positive regulation of cell cycle
inner ear development
regulation of mitochondrial membrane potential
positive regulation of protein kinase B signaling
cellular response to nitrosative stress
positive regulation of G1/S transition of mitotic cell cycle
regulation of mitochondrial DNA metabolic process
regulation of response to oxidative stress
positive regulation of cyclin-dependent protein kinase activity
positive regulation of otic vesicle morphogenesis
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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