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Invitrogen
ZNHIT1 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-99756
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human ZNHIT1(Accession O43257), corresponding to amino acid residues R21-T71.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total ZNHIT1.
Target Information
Seems to play a role in p53-mediated apoptosis induction (PubMed:17380123). Binds to NR1D2 and relieves it of its inhibitory effect on the transcription of APOC3 without affecting its DNA-binding activity (PubMed:17892483). [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: cyclin-G1-binding protein 1; H_DJ0747G18.14; p18 Hamlet; p18Hamlet; putative cyclin G1 interacting protein; unnamed protein product; zinc finger protein subfamily 4A member 1; zinc finger protein, subfamily 4A (HIT domain containing), member 1; zinc finger, HIT domain containing 1; zinc finger, HIT type 1; ZNHIT1
Gene Aliases: 2700001K05Rik; CG1I; p18(Hamlet); ZNFN4A1
UniProt ID: (Human) O43257, (Mouse) Q8R331
Entrez Gene ID: (Human) 10467, (Rat) 100360077, (Mouse) 70103
negative regulation of transcription from RNA polymerase II promoter
heart process
chromatin remodeling
biological_process
intestinal stem cell homeostasis
regulation of T cell proliferation
muscle cell differentiation
positive regulation of DNA damage response, signal transduction by p53 class mediator
positive regulation of gene expression, epigenetic
calcium ion homeostasis
positive regulation of transcription initiation from RNA polymerase II promoter
hematopoietic stem cell homeostasis
negative regulation of G0 to G1 transition
positive regulation of lymphoid progenitor cell differentiation
regulation of transcription, DNA-templated
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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