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PEP-126 is an 18 amino acid synthetic peptide whose sequence corresponds to residues 494-511 from rat COPI beta'. The sequence of this peptide is (amino to carboxy terminus): K (494)-V-L-A-A-Q-E-T-H-E-G-V-T-E-D-G-I-E (511).
This peptide may be used for neutralization and control experiments with the polyclonal antibody that reacts with this product and rat COPI beta', catalog # PA1-068. Using a solution of peptide of equal volume and concentration to the corresponding antibody will yield a large molar excess of peptide (~70-fold) for competitive inhibition of antibody-protein binding reactions.
Reconstitute with 0.1 mL of distilled water.
This gene encodes a protein subunit of the coatomer complex associated with non-clathrin coated vesicles. The coatomer complex, also known as the coat protein complex 1, forms in the cytoplasm and is recruited to the Golgi by activated guanosine triphosphatases. Once at the Golgi membrane, the coatomer complex may assist in the movement of protein and lipid components back to the endoplasmic reticulum. Alternatively spliced transcript variants have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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