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PEP-275 is a 15 amino acid synthetic peptide whose sequence corresponds to residues 843-857 of rat SREBP 2. The sequence of this peptide is (amino to carboxy terminus): A ( 843)-I-S-W-L-Q-G-D-D-A-A-V-R-S-H (857)
This peptide may be used for neutralization and control experiments with the polyclonal antibody that reacts with this product, SREBP 2, catalog # PA1-338. Using a solution of peptide of equal volume and concentration to the corresponding antibody will yield a large molar excess of peptide (~70-fold) for competitive inhibition of antibody-protein binding reactions.
Reconstitute with 0.1 mL of distilled water.
This gene encodes a ubiquitously expressed transcription factor that controls cholesterol homeostasis by stimulating transcription of sterol-regulated genes. The encoded protein contains a basic helix-loop-helix-leucine zipper (bHLH-Zip) domain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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