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Invitrogen
Rat VDP (aa 1-17) Synthetic Peptide
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Product Details
PEP-276
Product Specifications
Class
Synthetic
Type
Peptide
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Lyophilized
Concentration
0.5 mg/mL
Amount
50 µg
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
PEP-276 is a 17 amino acid synthetic peptide whose sequence corresponds to residues 1-17 of rat p115. The sequence of this peptide is (amino to carboxy terminus): M (1)-N-F-L-R-G-V-M-G-G-Q-S-A-G-P-Q- H (17)
This peptide may be used for neutralization and control experiments with the polyclonal antibody that reacts with this product, p115, catalog # PA1-006. Using a solution of peptide of equal volume and concentration to the corresponding antibody will yield a large molar excess of peptide (~70-fold) for competitive inhibition of antibody-protein binding reactions.
Reconstitute with 0.1 mL of distilled water.
Target Information
The protein encoded by this gene is a peripheral membrane protein which recycles between the cytosol and the Golgi apparatus during interphase. It is regulated by phosphorylation: dephosphorylated protein associates with the Golgi membrane and dissociates from the membrane upon phosphorylation. Ras-associated protein 1 recruits this protein to coat protein complex II (COPII) vesicles during budding from the endoplasmic reticulum, where it interacts with a set of COPII vesicle-associated SNAREs to form a cis-SNARE complex that promotes targeting to the Golgi apparatus. Transport from the ER to the cis/medial Golgi compartments requires the action of this gene product, GM130 and giantin in a sequential manner.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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