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Invitrogen
Human/Mouse FOXC1 Synthetic Peptide
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Product Details
PEP-298
Product Specifications
Class
Synthetic
Type
Peptide
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Lyophilized
Concentration
1 mg/mL once reconstituted
Amount
50 µg
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
This peptide corresponds to amino acids A(423) VDDPLPDYSLP (434) of human FOXC1 (corresponds to mouse FOXC1 aa 430-440) and can be used as a blocking peptide with polyclonal antibody PA1-807.
Target Information
FOXC1 is a protein belonging to the forkhead family of transcription factors which is characterized by a distinct DNA-binding forkhead domain. The specific function of this protein is not known, however, it plays a role in the regulation of FGF19-FGFR4-MAPK pathway to promote both the development and maintenance of anterior segment structures within the eye. Mutations in this gene cause various glaucoma, iridogoniodysgenesis anomaly, Peters anomaly that includes central corneal leukoma, absence of the posterior corneal stroma and Descemetmembrane and Axenfeld-Rieger anomaly characterized by posterior corneal embryotoxon, iris adhesion to the Schwalbe line, hypertelorism, hypoplasia of the malar bones, congenital absence of some teeth and mental retardation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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