DCDIEGKDGK QYESVLMVSI DQLLDSMKEI GSNCLNNEFN FFKRHICDAN KEGMFLFRAA RKLRQFLKMN STGDFDLHLL KVSEGTTILL NCTGQVKGRK PAALGEAQPT KSLEENKSLK EQKKLNDLCF LKRLLQEIKT CWNKILMGTK EH

Molecular weight

17.5 kDa

Class

Recombinant

Type

Protein

Purity

>95% by SDS-PAGE

Endotoxin concentration

<0.1 ng/µg

Activity

ED50 = 0.2 - 1 ng/mL; determined by the dose-dependent proliferation of human PBMCs.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Amount

25 µg

Purification

purified

Contains

no preservative

Storage conditions

4°C

Shipping conditions

Wet ice (domestic); Wet or Dry ice (international)

Product Specific Information

Carrier-Free

Reconstitution: Centrifuge the vial briefly, before opening to bring the contents to the bottom. Reconstitute the lyophilized protein in sterile, distilled water to 0.1-1.0 mg/mL to regain full activity. Apportion the reconstituted protein into working aliquots and store at ≤-20°C. Make any further dilutions of the reconstituted protein in low endotoxin medium or buffered solution with FBS or tissue culture grade BSA.

Storage: Store the lyophilized protein at 2-8°C, preferably desiccated. Upon reconstitution, apportion into working aliquots and store at ≤-20°C (not in a frost-free freezer). Avoid repeated freeze-thaw cycles.

Target Information

Interleukin 7 (IL-7) is a hematopoietic cytokine that is constitutively produced by stromal cells from the bone marrow and thymus. IL-7 signals through the IL-7R to promote the differentiation of hematopoietic stem cells to lymphoid precursor cells, which give rise to T cells, B cells, and natural killer cells.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: CD127; CD127 antigen; CDw127; cytokine; H-IL-7; IL-7; IL-7 receptor subunit alpha; IL-7R subunit alpha; IL7R; IL-7 receptor alpha chain; ILN; Interleukin; interleukin 7 precursor; interleukin 7 receptor alpha chain; Interleukin-7; interleukin-7 receptor precursor; Interleukin-7 receptor subunit alpha; Interleukin7; M-IL-7; soluble interleukin-7 receptor; unnamed protein product

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Gene Aliases: CD127; CDW127; IL-7; IL-7R-alpha; IL-7Ralpha; IL7; IL7R; IL7RA; IL7Ralpha; ILRA; IMD104; IMD130; lnc-IL7R; sIL-7R

Human IL-7 Recombinant Protein

Product Details

PHC0076

Bioactivity (Bioactivity)

Species

Published species

Expression System

Amino acid sequence