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Bruton tyrosine kinase (BTK) is a cytoplasmic tyrosine kinase belonging to the SRC-related TEC subfamily of tyrosine kinases. Mutations in the BTK gene have been linked to severe developmental blocks in human B-cell ontogeny and immunodeficiency disorders.
For Research Use Only. Not for use in diagnostic procedures.
Specifications
Accession Number
NP_000052
Molecular Weight
81.3 kDa
Quantity
100 µg
Source
Human
Gene Alias
BTK, ATK, XLA
KinaseFamily
TEC Kinase Family
Recombinant
Yes
Protein Tag
His Tag
Kinase Group
Tyrosine Kinases
Shipping Condition
Dry Ice
Expression System
Baculovirus
Protein Family
Kinases & Inhibitors
Protein Form
Full Length, Recombinant, Cytoplasmic
Form
Liquid
Protein Subtype
Cytoplasmic Tyrosine Kinases
Validated Application
Kinase Assay
Species
Human
Research Category
Oncology, Signal Transduction
Contents & Storage
Storage Buffer: 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.5 mM EDTA, 0.05% Triton X-100, 4 mM DTT, 50% glycerol
Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.
Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.